abstract：:Class II antigens are strongly expressed on the inflamed colonic epithelium in inflammatory bowel disease. However, the mechanism of this epithelial class II antigen induction is not fully understood. Increased activities of interferon (IFN)gamma, tumor necrosis factor (TNF)alpha, and interleukin (IL)2 have been shown...

journal_title：Journal of gastroenterology

authors： Horie Y,Chiba M,Suzuki T,Kudo T,Kamata A,Iizuka M,Masamune O

更新日期：1998-02-01 00:00:00

abstract：:Adult midgut rotational anomalies are difficult to diagnose. Any symptoms present in adults may be the result of intermittent volvulus of the midgut. Successful outcome of this clinical condition depends on prompt diagnosis and timely surgical intervention. Computed tomography (CT) is useful in early identification of...

journal_title：Journal of gastroenterology

authors： Wang TK,Yeh CH

更新日期：1998-02-01 00:00:00

abstract：:An expert meeting was organized by the Swedish and Norwegian Medical Products Agencies in September 1995 in order to review the current literature and opinions on detection and treatment of Helicobacter pylori. Ten people from these Agencies and 23 experts participated in the workshop and all were involved in the fina...

journal_title：Journal of gastroenterology

authors： Unge P

更新日期：1998-01-01 00:00:00

abstract：:Inflammatory cells in the gastric epithelium and direct cell damage are important effects of H. pylori infection in causing gastroduodenal diseases. The aim of this study was to determine whether H. Pylori possessing the cagA gene and vacuolating cytotoxin activity (cagA+/tox+) has these toxigenicities. The detection ...

journal_title：Journal of gastroenterology

authors： Kodama K,Fujioka T,Ito A,Kodama R,Nasu M

更新日期：1998-01-01 00:00:00

abstract：:We simultaneously recorded gastric emptying of radio-opaque markers (ROMs) and monitored serial changes in plasma acetaminophen (AAP) levels to demonstrate the relationship between the ROM and the AAP methods, and we investigated the effect of a single intravenous dose of erythromycin (EM) on gastric emptying in healt...

journal_title：Journal of gastroenterology

authors： Park HJ,Jung JK,Song KS,Lee SI,Itoh Z,Park IS

更新日期：1997-12-01 00:00:00

abstract：:Anomalous arrangement of the pancreaticobiliary ductal system (AAPB), a congenital anomaly defined as a union of the pancreatic and biliary ducts located outside the duodenal wall, is a newly designated disease entity, and is frequently found in adult patients with gallbladder carcinoma (GBX). In the present study, th...

journal_title：Journal of gastroenterology

authors： Yang Y,Fujii H,Matsumoto Y,Suzuki K,Kawaoi A,Suda K

更新日期：1997-12-01 00:00:00

abstract：:A 65-year-old woman was admitted to our hospital with the diagnosis of gallbladder tumor. Right extended hepatic lobectomy plus lymph node dissection of the hepatoduodenal ligament and left hepaticojejunostomy with Roux-en-Y reconstruction was performed in July, 1993. The gallbladder tumor was histologically proven to...

journal_title：Journal of gastroenterology

authors： Suganuma M,Marugami Y,Sakurai Y,Ochiai M,Hasegawa S,Imazu H,Matsubara T,Funabiki T,Kuroda M

更新日期：1997-12-01 00:00:00

abstract：:We assessed the influence of epidermal growth factor (EGF) and insulin on gastric epithelial restoration in vitro. Rabbit gastric epithelial cells were cultured and formed a complete monolayer cell sheet in 2 days. We created a wound (1.8 +/- 0.05 mm2) by denuding an area of cells, and EGF (0.1-30 ng/ml) and/or insuli...

journal_title：Journal of gastroenterology

authors： Maehiro K,Watanabe S,Hirose M,Iwazaki R,Miwa H,Sato N

更新日期：1997-10-01 00:00:00

abstract：:We report a case of gastric neuroendocrine (NE) carcinoma associated with chronic atrophic gastritis type A (CAG/A) or reversed atrophic type gastritis. A 9 x 6 cm tumor was resected from the stomach to control pain in a 55-year-old Japanese woman with peritoneal dissemination and metastatic tumors of the liver and ov...

journal_title：Journal of gastroenterology

authors： Kaizaki Y,Fujii T,Kawai T,Saito K,Kurihara K,Fukayama M

更新日期：1997-10-01 00:00:00

abstract：:Cowden's disease, multiple hamartoma syndrome, is a dominantly inherited disorder characterized by multiple hamartomas of ectodermal, endodermal, and mesodermal origin and also by a high incidence of malignant tumors. Despite many efforts to identify the genetic alterations responsible for the syndrome, the molecular ...

journal_title：Journal of gastroenterology

authors： Suzuki T,Ichinose M,Matsubara Y,Yahagi N,Kurokawa K,Fukamachi H,Miki K

更新日期：1997-10-01 00:00:00

abstract：:Small bowel transit time (SBTT) in 15 young and 13 elderly women was assessed by measuring breath hydrogen concentrations after they had consumed a solid test meal. The meal consisted of 200 g cooked rice, 50 ml miso (made from fermented soy bean curd) soup, a boiled egg, and 95.5 g of cooked soy beans with mixed vege...

journal_title：Journal of gastroenterology

authors： Kagaya M,Iwata N,Toda Y,Nakae Y,Kondo T

更新日期：1997-08-01 00:00:00

abstract：:To assess the efficacy of the zinostatin derivative, the anti-tumor agent, styrene-maleic acid neocarzinostatin, in treating multiple small liver cancers, 29 patients with multiple hepatocellular carcinoma of 3 cm or less in diameter were treated with intraarterial injections of this high molecular weight agent, mixed...

journal_title：Journal of gastroenterology

authors： Ikeda K,Saitoh S,Suzuki Y,Tsubota A,Koida I,Kobayashi M,Arase Y,Chayama K,Murashima N,Kumada H

更新日期：1997-08-01 00:00:00

abstract：:A 60-year-old woman was admitted to our department for detailed examination of a polypoid lesions of the gallbladder detected at the time of a mass survey by ultrasound. Endoscopic ultrasonography (EUS) demonstrated a broad-based mass lesion, about 10 mm in size, with an irregular surface, at the peritoneal side of th...

journal_title：Journal of gastroenterology

authors： Fujita N,Noda Y,Kobayashi G,Kimura K,Yago A,Okaniwa S

更新日期：1997-08-01 00:00:00

abstract：:Strain differences in the susceptibility of rats to induction of intestinal metaplasia by X-irradiation were examined. The gastric regions of 5-week-old males of five inbred strains of rats (F344/NSlc, Copenhagen, Buffalo/NacJcl, and ACI/NHos) and three strains of randomly bred rats (HOS:Donryu, Slc:Wistar, Slc:SD) we...

journal_title：Journal of gastroenterology

authors： Watanabe H,Fujimoto N,Masaoka Y,Ohtaki M,Ito A

更新日期：1997-06-01 00:00:00

abstract：:To evaluate the diagnostic utility of blood biochemical parameters in assessing degree of hepatic fibrosis, serum levels of aminoterminal type III procollagen peptide (P III P), type IV collagen (IV-collagen), 7S domain of type IV collagen (7S-collagen), and hyaluronan (HA) were measured in 54 patients with chronic vi...

journal_title：Journal of gastroenterology

authors： Takamatsu S,Nakabayashi H,Okamoto Y,Nakano H

更新日期：1997-06-01 00:00:00

abstract：:The present study was carried out to examine the effects of submucosal administration of endothelin on gastric mucosal integrity in rats. Injection of endothelin-3 into the submucosal space of the stomach induced gastric mucosal damage dose-dependently and site-specifically. The gastric injury was localized only at th...

journal_title：Journal of gastroenterology

authors： Watanabe Y,Okumura T,Harada K,Kohgo Y

更新日期：1997-04-01 00:00:00

abstract：:Interleukin 6 (IL-6) is a pleiotropic cytokine produced by a wide variety of lymphoid and non-lymphoid tissues. We studied the relationship between IL-6 and the liver in an attempt to elucidate this cytokine's role in hepatitis C-induced liver inflammation. We investigated the behavior of serum IL-6 in 25 patients wit...

journal_title：Journal of gastroenterology

authors： Malaguarnera M,Di Fazio I,Romeo MA,Restuccia S,Laurino A,Trovato BA

更新日期：1997-04-01 00:00:00

abstract：:We report a case of synchronous gas gangrene and spontaneous bacterial peritonitis associated with liver cirrhosis. The patient was a 52-year-old man who was being followed for decompensated liver cirrhosis. He experienced sudden onset lower abdominal pain with distension and pain in the left leg. A bullous lesion, wi...

journal_title：Journal of gastroenterology

authors： Murata K,Shimizu A,Takase K,Nakano T,Tameda Y

更新日期：1997-04-01 00:00:00

abstract：:A retrospective long-term endoscopic follow-up study was designed to examine atrophic changes in the gastric mucosa over time in Helicobacter pylori-positive patients. Over a period of 8-17 years (mean, 13.4 years) 22 subjects (5 men, 17 women, mean age, 55 years) without localized gastroduodenal lesions underwent ser...

journal_title：Journal of gastroenterology

authors： Sakaki N,Arakawa T,Katou H,Momma K,Egawa N,Kamisawa T,Yamada Y,Tu Y,Ishikawa C,Ishiwata J

更新日期：1997-02-01 00:00:00

abstract：:A 27-year-old woman with a 9-year history of ulcerative colitis involving the entire colon was admitted to our hospital in August 1992 because of bloody stools and left lower abdominal pain. She had been treated with sulfasalazine since 1983 and the colitis had been clinically quiescent or mild for 7 years. She had al...

journal_title：Journal of gastroenterology

authors： Seo M,Okada M,Osamura S,Hara S,Umeno T,Maeshiro K,Yamada Y,Yuh K

更新日期：1997-02-01 00:00:00

abstract：:Primary sclerosing cholangitis is very rare in Japan. The aim of the present study was to identify the characteristics of such patients in Japan. A questionnaire was sent to the members of the Japanese Society of Gastroenterology and responses for 192 cases were analyzed. There was male predominancy (61%), and two pea...

journal_title：Journal of gastroenterology

authors： Takikawa H,Manabe T

更新日期：1997-02-01 00:00:00

abstract：:We investigated the therapeutic effects of egualen sodium (KT1-32), a new antiulcer agent, on chronic erosive and atrophic gastritis induced by 5 months' administration of sodium taurocholate (TCA; 5 mM) in rats. The chronic gastritis was manifested by mucosal surface injuries (erosions), reduced mucosal thickness, re...

journal_title：Journal of gastroenterology

authors： Mochizuki S,Matsumoto M,Wakabayashi S,Kosakai K,Tomiyama A,Kishimoto S

更新日期：1996-12-01 00:00:00

abstract：:We report the coexistence of symptomatic viral, bacterial, and fungal infection of the upper gastrointestinal tract in a heart transplant recipient. Endoscopic findings were normal at all levels but, because of severe symptoms and recent conversion to positive serology for Cytomegalovirus, biopsies were taken. These s...

journal_title：Journal of gastroenterology

authors： Huwez FU,McPhaden AR,Belcher PR,Naik SK,Wheatley DJ

更新日期：1996-12-01 00:00:00

abstract：:Prevention of human diseases has become a major focus of biomedical investigators around the world. Our current screening and treatment regimens for colorectal cancer are not effective, as indicated by the fact that this disease is the second leading cause of death from cancer in the United States. Recently published ...

journal_title：Journal of gastroenterology

authors： DuBois RN,Smalley WE

更新日期：1996-12-01 00:00:00

abstract：:Our objective was to determine whether the prevalence of vacuolating cytotoxin production differed among Helicobacter pylori isolates obtained from patients with chronic gastritis, gastric ulcer, or duodenal ulcer. We examined the vacuolating cytotoxin production of 114 clinical H. pylori isolates in rabbit gastic epi...

journal_title：Journal of gastroenterology

authors： Kodama K,Fujioka T,Ito A,Kubota T,Murakami K,Nasu M

更新日期：1996-11-01 00:00:00

abstract：:We reviewed reports on the efficacy of clarithromycin in eradicating Helicobacter pylori. Reports on dual and 1-week triple therapy that included clarithromycin were analyzed to assess the eradication rates of H. pylori infection. Dual therapy with clarithromycin and a proton pump inhibitor achieved eradication rates ...

journal_title：Journal of gastroenterology

authors： Satoh K,Kimura K,Takimoto T,Kihira K,Taniguchi Y,Saifuku K

更新日期：1996-11-01 00:00:00

abstract：:Soft drinks containing dietary fiber are popular in Japan. There seem to be two types, one containing polydextrose and the other, oligosaccharide. These beverages are claimed to be useful for constipation or obesity, but data are scanty. We examined four such fiber-containing beverages [Fibe-mini Otsuka Pharmaceutical...

journal_title：Journal of gastroenterology

authors： Kondo T,Nakae Y

更新日期：1996-10-01 00:00:00

abstract：:We treated a patient with a mechanical ileus resulting from encasement of a loop of the small intestine by the great omentum, caused by abnormal adhesion. Apart from its occurrence postoperatively with laparotomy, strangulation of small intestine into the omentum is very rare, and its occurrence without underlying dis...

journal_title：Journal of gastroenterology

authors： Kimura H,Earashi M,Konishi K,Tsuneda A,Tazawa K,Inoue T,Maeda K,Yabushita K,Kuroda Y,Tsuji M,Miwa A

更新日期：1996-10-01 00:00:00

abstract：:Inconsistencies and omissions in current explanations for the well known depressions of gastric acid secretion and blood gastrin levels following acidification by antral stimulants are discussed. Evidence is presented which favors a reciprocal sensitivity relationship between the fundic mucosa and the antral G cells, ...

journal_title：Journal of gastroenterology

authors： Magee DF

更新日期：1996-10-01 00:00:00

abstract：:The requirement for well spread out chromosomes for the cytogenetic analysis of primary gastrointestinal tumors led us to develop new techniques. These techniques involved two main procedures: (1) preliminary incubation with culture medium in the presence of collagenase, Dispase, and colcemid, for 3 h, and (2) treatme...

journal_title：Journal of gastroenterology

authors： Sasai K,Tanaka R,Kawamura M,Honjo K,Matsunaga N,Nakada T,Homma K,Fujimura H

更新日期：1996-08-01 00:00:00

abstract：:We investigated the effect of intravenous infusions of the therapeutically available amino acid solutions Moripron and Morihepamin (Roussel Morishita, Osaka, Japan) on gallbladder contraction and cholecystokinin (CCK) release in healthy male volunteers. Plasma CCK levels were measured by radioimmunoassay, using the an...

journal_title：Journal of gastroenterology

authors： Shirohara H,Tabaru A,Otsuki M

更新日期：1996-08-01 00:00:00

abstract：:We report a case of Cruveihier-Baumgarten syndrome associated with portal vein thrombosis that developed, slowly during a 2-year period after endoscopic variceal sclerotherapy. The thrombosis led to the disappearance of the venous hum and the dilated abdominal wall veins characteristic of this syndrome. A 73-year-old ...

journal_title：Journal of gastroenterology

authors： Yamakawa O,Ohta H,Watanabe H,Motoo Y,Okai T,Kadoya M,Matsui O,Sawabu N

更新日期：1996-08-01 00:00:00

abstract：:To determine the role of endogenous substance P in ethanol-induced mucosal damage, two experiments were performed. In the first experiment, the stomachs of anesthetized rats were doubly cannulated and gastric damage was induced with 5ml of 30% ethanol in the gastric lumen. The damage was ameliorated by pretreatment wi...

journal_title：Journal of gastroenterology

authors： Hayashi H,Nishiyama K,Majima M,Katori M,Saigenji K

更新日期：1996-06-01 00:00:00

abstract：:The purpose of the present study was to elucidate the effect of hepatic reflow following ischemia on the remnant liver after hepatectomy with occluded hepatic blood inflow in dogs with obstructive jaundice. When 40% hepatectomy was performed with 10-min occlusion of hepatic blood inflow in dogs with obstructive jaundi...

journal_title：Journal of gastroenterology

authors： Ogura Y,Takagi K,Kawarada Y,Mizumoto R

更新日期：1996-06-01 00:00:00

abstract：:We encountered a patient with a ciliated hepatic foregut cyst with accompanying liver cirrhosis, which was hard to distinguish from well-differentiated hepatocellular carcinoma. A lesion 2 cm in diameter was found in the subcapsular region of the medial segment of the liver. It was slightly hypoechoic on ultrasonograp...

journal_title：Journal of gastroenterology

authors： Murakami T,Imai A,Nakamura H,Tsuda K,Kanai T,Wakasa K

更新日期：1996-06-01 00:00:00

abstract：:The proliferative activity of serrated adenomas of the large intestine was determined by examining proliferating cell nuclear antigen (PCNA). The PCNA labeling index, determined by visual inspection, and the PCNA area rate, determined with the newly developed image processor for analytical pathology (IPAP), of serrate...

journal_title：Journal of gastroenterology

authors： Fujishima N

更新日期：1996-04-01 00:00:00

abstract：:A rare case of benign diaphragmatic schwannoma in a 38-year-old female is reported. Precontrast computed tomography (CT) showed an encapsulated well-defined round homogeneous tumor with central calcification, measuring approximately 5 cm in diameter, arising from the left diaphragm. Contrast-enhanced CT and gadolinium...

journal_title：Journal of gastroenterology

authors： Koyama S,Araki M,Suzuki K,Fukutomi H,Maruyama T,Mun Y,Otsuka M,Fukao K

更新日期：1996-04-01 00:00:00

abstract：:The incidence and prevalence of primary biliary cirrhosis show wide geographic differences. The frequency of this disease in Japan is lower than in Northern Europe. To elucidate the immunoreactivity of serum with enzymes of the 2-oxo-acid dehydrogenase complex (2-OADC) and the M2 mitochondrial antigenic complex in Jap...

journal_title：Journal of gastroenterology

authors： Omagari K,Rowley MJ,Jois JA,Feeney SJ,Komatsu K,Maeda T,Onishi S,Yamazaki K,Suzuki K,Galperin C,Mackay IR

更新日期：1996-02-01 00:00:00

abstract：:A 55-year-old woman was treated at our hospital for multiple sclerosis. Therapy consisted of glucocorticosteroids and cyclosporin. In the 7th week after these drugs were discontinued the patient developed acute liver failure due to fulminant hepatitis (FH) and died. Post-mortem examination showed massive liver necrosi...

journal_title：Journal of gastroenterology

authors： Funaoka M,Kato K,Komatsu M,Ono T,Hoshino T,Kato J,Kuramitsu T,Ishii T,Toyoshima I,Masamune O

更新日期：1996-02-01 00:00:00

abstract：:To elucidate the role played by hepatic sinusoidal cells in the regulation of the circulatory status in the liver, the effect of endothelins (ETs) on primary-cultured stellate cells was examined. Kinetic analysis with 125I-labeled ET-1 revealed that stellate cells have ET receptors with a Kd value of 141 pM and a Bmax...

journal_title：Journal of gastroenterology

authors： Kawada N,Kuroki T,Kobayashi K,Inoue M,Kaneda K,Decker K

更新日期：1995-12-01 00:00:00